5JH5
Structural Basis for the Hierarchical Assembly of the Core of PRC1.1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 2B | polymer | 281 | 32494.6 | 1 | UniProt (Q8NHM5) Pfam (PF12937) Pfam (PF25372) | Homo sapiens (Human) | CXXC-type zinc finger protein 2,F-box and leucine-rich repeat protein 10,F-box protein FBL10,F-box/LRR-repeat protein 10,JmjC domain-containing histone demethylation protein 1B,Jumonji domain-containing EMSY-interactor methyltransferase motif protein,Protein JEMMA,Protein-containing CXXC domain 2,[Histone-H3]-lysine-36 demethylase 1B |
| 2 | B (B) | S-phase kinase-associated protein 1 | polymer | 162 | 18689.5 | 1 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) | Homo sapiens (Human) | Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
| 3 | C (C) | Polycomb group RING finger protein 1 | polymer | 109 | 13205.9 | 1 | UniProt (Q9BSM1) Pfam (PF16207) | Homo sapiens (Human) | Nervous system Polycomb-1,NSPc1,RING finger protein 68 |
| 4 | D (D) | BCL-6 corepressor-like protein 1 | polymer | 122 | 14164.6 | 1 | UniProt (Q5H9F3) Pfam (PF16553) | Homo sapiens (Human) | BCoR-like protein 1 |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 1059 - 1336 (UniProt: Q8NHM5)
C: 150 - 255 (UniProt: Q9BSM1)
D: 1594 - 1711 (UniProt: Q5H9F3)
| PDB | External Database | Details |
|---|---|---|
| Gly 1056 | - | expression tag |
| Thr 1057 | - | expression tag |
| Arg 1058 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 147 | - | expression tag |
| Thr 148 | - | expression tag |
| Arg 149 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Mse 1590 | - | initiating methionine |
| Glu 1591 | - | expression tag |
| Thr 1592 | - | expression tag |
| Arg 1593 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78554.6 | |
| All* | Total formula weight | 78554.6 |
