6DJW

Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex

Summary for 6DJW

• Entry DOI: 10.2210/pdb6djw/pdb
• Descriptor: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (4 entities in total)
• Functional Keywords: ubiquitin, e3 ligase, e2 conjugating enzyme, phosphorylation, mitophagy, parkinson disease, transferase
• Biological source: Bactrocera dorsalis (Oriental fruit fly); More
• Total number of polymer chains: 3
• Total formula weight: 66676.13

Authors

Sauve, V.,Sung, G.,Trempe, J.F.,Gehring, K. (deposition date: 2018-05-26, release date: 2018-07-04, Last modification date: 2023-10-11)

• Primary citation: Sauve, V.,Sung, G.,Soya, N.,Kozlov, G.,Blaimschein, N.,Miotto, L.S.,Trempe, J.F.,Lukacs, G.L.,Gehring, K.; Mechanism of parkin activation by phosphorylation.; Nat. Struct. Mol. Biol., 25:623-630, 2018; PubMed: 29967542; DOI: 10.1038/s41594-018-0088-7

Experimental method

X-RAY DIFFRACTION (3.801 Å)