6NIF
crystal structure of human REV7-RAN complex
Summary for 6NIF
| Entry DOI | 10.2210/pdb6nif/pdb |
| Descriptor | hREV7, GTP-binding nuclear protein Ran, hREV3 fusion (2 entities in total) |
| Functional Keywords | small gtpase, mad2l2, cell cycle |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 28728.14 |
| Authors | Wang, X.,Pertz, L.,Hua, D.P.,Zhang, T.Q.,Listovsky, T.,Xie, W. (deposition date: 2018-12-27, release date: 2019-09-11, Last modification date: 2023-10-11) |
| Primary citation | Wang, X.,Pernicone, N.,Pertz, L.,Hua, D.,Zhang, T.,Listovsky, T.,Xie, W. REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294:15733-15742, 2019 Cited by PubMed: 31484720DOI: 10.1074/jbc.RA119.010123 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.002 Å) |
Structure validation
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