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6DJX

Crystal Structure of pParkin-pUb-UbcH7 complex

Summary for 6DJX
Entry DOI10.2210/pdb6djx/pdb
DescriptorRBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (4 entities in total)
Functional Keywordsubiquitin, e3 ligase, e2 conjugating enzyme, phosphorylation, mitophagy, parkinson disease, transferase
Biological sourceBactrocera dorsalis (Oriental fruit fly)
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Total number of polymer chains3
Total formula weight76121.70
Authors
Sauve, V.,Sung, G.,Trempe, J.F.,Gehring, K. (deposition date: 2018-05-27, release date: 2018-07-04, Last modification date: 2023-10-11)
Primary citationSauve, V.,Sung, G.,Soya, N.,Kozlov, G.,Blaimschein, N.,Miotto, L.S.,Trempe, J.F.,Lukacs, G.L.,Gehring, K.
Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25:623-630, 2018
Cited by
PubMed: 29967542
DOI: 10.1038/s41594-018-0088-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (4.801 Å)
Structure validation

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