PDB: 6405 件ウェブページステータス検索Chemie searchBIRD

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7PDW	Crystal structure of parent TCR (728) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. 登録日 2021-08-09 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022
7UR1	SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01 分子名称: Beta-2-microglobulin, HLA class I antigen, SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) 著者 Szeto, C, Ahn, Y.M, Gras, S. 登録日 2022-04-21 公開日 2023-04-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01 To Be Published
7UM2	SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01 分子名称: Beta-2-microglobulin, CADMIUM ION, HLA class I antigen, ... 著者 Szeto, C, Gras, S. 登録日 2022-04-06 公開日 2023-04-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01 To Be Published
7QNG	Structure of a MHC I-Tapasin-ERp57 complex 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R. 登録日 2021-12-20 公開日 2022-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity. Nat Commun, 13, 2022
7QPD	Structure of the human MHC I peptide-loading complex editing module 分子名称: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ... 著者 Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R. 登録日 2022-01-03 公開日 2022-07-20 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (3.73 Å) 主引用文献 Molecular basis of MHC I quality control in the peptide loading complex. Nat Commun, 13, 2022
7QPJ	Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. 登録日 2022-01-04 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022
4EUP	The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Hossain, M, Baker, B.M. 登録日 2012-04-25 公開日 2013-05-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural description of how different MART-1 antigenic peptides influence JKF6 T cell receptor recognition To be Published
7UC5	Crystal Structure of HLA A*0301 in complex with ILRGSVAHK, a 9-mer epitope from Influenza A 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... 著者 Gras, S, Nguyen, A.T, Szeto, C. 登録日 2022-03-16 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 CD8+ T cells cross-recognise conserved influenza A and B homologous epitopes to be published
7UMG	Crystal structure of human CD8aa-MR1-Ac-6-FP complex 分子名称: Beta-2-microglobulin, CHLORIDE ION, Major histocompatibility complex class I-related gene protein, ... 著者 Awad, W, Rossjohn, J. 登録日 2022-04-06 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J.Exp.Med., 219, 2022
5NQK	human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D. 登録日 2017-04-20 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 To Be Published
7UFJ	Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR 分子名称: 3-ethoxy-4-hydroxybenzaldehyde, ACETATE ION, Beta-2-microglobulin, ... 著者 Wang, C.J, Rossjohn, J, Le Nours, J. 登録日 2022-03-22 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1. J.Biol.Chem., 298, 2022
4E5X	Crystal structure of a complex between the human adenovirus type 2 E3-19K protein and MHC class I molecule HLA-A2/Tax 分子名称: Beta-2-microglobulin, Early E3 18.5 kDa glycoprotein, HLA class I histocompatibility antigen, ... 著者 Li, L, Bouvier, M. 登録日 2012-03-14 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulation. Nat.Struct.Mol.Biol., 19, 2012
4EN3	Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ... 著者 Lopez-Sagaseta, J, Adams, E.J. 登録日 2012-04-12 公開日 2012-10-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.568 Å) 主引用文献 The Molecular Basis for Recognition of CD1d/alpha-Galactosylceramide by a Human Non-Valpha24 T Cell Receptor Struct. Title Plos Biol., 10, 2012
7XF3	The structure of HLA-B*1501/BM58-66AF9 分子名称: 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen 著者 Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. 登録日 2022-03-31 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
5OPI	Crystal structure of the TAPBPR-MHC I peptide editing complex 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Thomas, C, Tampe, R. 登録日 2017-08-09 公開日 2017-10-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing. Science, 358, 2017
7WZZ	Crystal structure of peptide KAGQVVTIW in complex with HLA-B5801 分子名称: Beta-2-microglobulin, GLYCEROL, LYS-ALA-GLY-GLN-VAL-VAL-THR-ILE-TRP, ... 著者 Huan, X, Ren, E.C. 登録日 2022-02-20 公開日 2023-05-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.305 Å) 主引用文献 Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep, 13, 2023
7X00	Crystal structure of peptide VSFIEFVGW in complex with HLA-B5801 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Huan, X, Ren, E.C. 登録日 2022-02-20 公開日 2023-05-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep, 13, 2023
7X1B	Crystal structure of peptide KAGQVVTI in complex with HLA-B5801 分子名称: Beta-2-microglobulin, GLYCEROL, HLA-B, ... 著者 Huan, X, Ren, E.C. 登録日 2022-02-23 公開日 2023-05-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep, 13, 2023
7X1C	Crystal structure of peptide VSFIEFVI in complex with HLA-B5801 分子名称: Beta-2-microglobulin, GLYCEROL, HLA-B, ... 著者 Huan, X, Ren, E.C. 登録日 2022-02-23 公開日 2023-05-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.409 Å) 主引用文献 Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01. Sci Rep, 13, 2023
4F7T	Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505) 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... 著者 Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. 登録日 2012-05-16 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals. J.Virol., 86, 2012
6EQB	HLA class I histocompatibility antigen 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... 著者 Rizkallah, P.J, Cole, D.K. 登録日 2017-10-12 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 TCR-induced alteration of primary MHC peptide anchor residue. Eur.J.Immunol., 49, 2019
6ENY	Structure of the human PLC editing module 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ... 著者 Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R. 登録日 2017-10-07 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structure of the human MHC-I peptide-loading complex. Nature, 551, 2017
6RPB	Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. 登録日 2019-05-14 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
6RP9	Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV 分子名称: Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ... 著者 Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. 登録日 2019-05-14 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
6EQA	HLA class I histocompatibility antigen 分子名称: ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K. 登録日 2017-10-12 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 TCR-induced alteration of primary MHC peptide anchor residue. Eur.J.Immunol., 49, 2019

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