4EUP

The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide

Summary for 4EUP

• Entry DOI: 10.2210/pdb4eup/pdb
• Related: 4EUQ 4EUR
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Melanoma antigen recognized by T-cells 1, ... (6 entities in total)
• Functional Keywords: nonapeptide, mhc class i, cross-reactivity, melanoma, cancer, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769; Endoplasmic reticulum membrane; Single-pass type III membrane protein: Q16655
• Total number of polymer chains: 10
• Total formula weight: 189678.94

Authors

Hossain, M.,Baker, B.M. (deposition date: 2012-04-25, release date: 2013-05-01, Last modification date: 2024-10-30)

• Primary citation: Hossain, M.,Baker, B.M.; Structural description of how different MART-1 antigenic peptides influence JKF6 T cell receptor recognition; To be Published,

Experimental method

X-RAY DIFFRACTION (2.88 Å)