4EUP

The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (D, A)	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	275	31854.2	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439)	Homo sapiens (human)	HLA-A*0201 heavy chain, MHC class I antigen A*2
2	B, E (E, B)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C, F (F, C)	Melanoma antigen recognized by T-cells 1	polymer	9	856.1	2	UniProt (Q16655)	Homo sapiens	MART-1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A
4	G, H (G, I)	JKF6 alpha chain	polymer	206	22472.6	2		Homo sapiens (human)
5	I, J (H, J)	JKF6 beta chain	polymer	243	27777.2	2		Homo sapiens (human)
6	K, L, M, N, O... (D, E, A, B, G...)	water	water		18.0	86	Chemie (HOH)

Sequence modifications

E, B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

F, C: 1 - 9 (UniProt: Q16655)

PDB	External Database	Details
Leu 2	Ala 28	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	189678.9
All*	Total formula weight	189678.9

*Water molecules are not included.