4EUP
The complex between TCR JKF6 and human Class I MHC HLA-A2 presenting the MART-1(27-35)(A27L) peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, A | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (human) | HLA-A*0201 heavy chain, MHC class I antigen A*2 |
2 | E, B | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | |
3 | F, C | Melanoma antigen recognized by T-cells 1 | polymer | 9 | 856.1 | 2 | UniProt (Q16655) In PDB | Homo sapiens | MART-1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A |
4 | G, I | JKF6 alpha chain | polymer | 206 | 22472.6 | 2 | Homo sapiens (human) | ||
5 | H, J | JKF6 beta chain | polymer | 243 | 27777.2 | 2 | Homo sapiens (human) | ||
6 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
E, B: 1 - 99 (UniProt: P61769)
F, C: 1 - 9 (UniProt: Q16655)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Leu 2 | Ala 28 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 189678.9 | |
All* | Total formula weight | 189678.9 |