7UMG
Crystal structure of human CD8aa-MR1-Ac-6-FP complex
Summary for 7UMG
Entry DOI | 10.2210/pdb7umg/pdb |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, T-cell surface glycoprotein CD8 alpha chain, ... (7 entities in total) |
Functional Keywords | cd8 coreceptor, mr1, metabolite presentation, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 72795.20 |
Authors | Awad, W.,Rossjohn, J. (deposition date: 2022-04-06, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Souter, M.N.T.,Awad, W.,Li, S.,Pediongco, T.J.,Meehan, B.S.,Meehan, L.J.,Tian, Z.,Zhao, Z.,Wang, H.,Nelson, A.,Le Nours, J.,Khandokar, Y.,Praveena, T.,Wubben, J.,Lin, J.,Sullivan, L.C.,Lovrecz, G.O.,Mak, J.Y.W.,Liu, L.,Kostenko, L.,Kedzierska, K.,Corbett, A.J.,Fairlie, D.P.,Brooks, A.G.,Gherardin, N.A.,Uldrich, A.P.,Chen, Z.,Rossjohn, J.,Godfrey, D.I.,McCluskey, J.,Pellicci, D.G.,Eckle, S.B.G. CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J.Exp.Med., 219:-, 2022 Cited by PubMed: 36018322DOI: 10.1084/jem.20210828 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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