5OPI

Crystal structure of the TAPBPR-MHC I peptide editing complex

Summary for 5OPI

Entry DOI	10.2210/pdb5opi/pdb
Descriptor	H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, TAP binding protein-like variant (3 entities in total)
Functional Keywords	adaptive immunity, antigen processing, antigen presentation, peptide proofreading, immune system
Biological source	Mus musculus (Mouse) More
Cellular location	Membrane; Single-pass type I membrane protein: P01899 Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains	3
Total formula weight	83779.87
Authors	Thomas, C.,Tampe, R. (deposition date: 2017-08-09, release date: 2017-10-18, Last modification date: 2024-01-17)
Primary citation	Thomas, C.,Tampe, R. Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing. Science, 358:1060-1064, 2017 Cited by PubMed: 29025996 DOI: 10.1126/science.aao6001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation