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7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-14
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEU
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BU of 7leu by Molmil
Structure of importin a2 bound to p65-NLS
分子名称: Importin subunit alpha-1, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
3ZJY
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BU of 3zjy by Molmil
Crystal Structure of Importin 13 - RanGTP - eIF1A complex
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ...
著者Gruenwald, M, Lazzaretti, D, Bono, F.
登録日2013-01-21
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
6MJL
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BU of 6mjl by Molmil
Crystal structure of ChREBP NLS peptide bound to importin alpha.
分子名称: ChREBP Peptide ASN-TYR-TRP-LYS-ARG-ARG-ILE-GLU-VAL, Importin subunit alpha-1
著者Jung, H, Uyeda, K.
登録日2018-09-21
公開日2019-09-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of importin alpha and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin alpha interactions.
Biochem.J., 477, 2020
1IBR
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BU of 1ibr by Molmil
COMPLEX OF RAN WITH IMPORTIN BETA
分子名称: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ...
著者Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A.
登録日1999-05-14
公開日1999-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Cell(Cambridge,Mass.), 97, 1999
1QGR
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BU of 1qgr by Molmil
STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH)
分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT)
著者Cingolani, G, Petosa, C, Weis, K, Muller, C.W.
登録日1999-05-04
公開日1999-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
1QGK
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BU of 1qgk by Molmil
STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA
分子名称: PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT)
著者Cingolani, G, Petosa, C, Weis, K, Muller, C.W.
登録日1999-04-29
公開日1999-05-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
5H43
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BU of 5h43 by Molmil
Structural and mechanistical studies of the nuclear import by Importin-alpha
分子名称: Histone acetyltransferase KAT8, Importin subunit alpha-1
著者Wang, R, Li, Y.
登録日2016-10-28
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Traffic, 19, 2018
2X19
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BU of 2x19 by Molmil
Crystal structure of Importin13 - RanGTP complex
分子名称: GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ...
著者Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E.
登録日2009-12-23
公開日2010-02-16
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
3UKW
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BU of 3ukw by Molmil
Mouse importin alpha: Bimax1 peptide complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKX
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BU of 3ukx by Molmil
Mouse importin alpha: Bimax2 peptide complex
分子名称: Bimax2 peptide, Importin subunit alpha-2
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
8TUV
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BU of 8tuv by Molmil
Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2
分子名称: 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE
著者Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
8HE3
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BU of 8he3 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751)
分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1, SULFATE ION
著者Matsuura, Y.
登録日2022-11-07
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
8HE0
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BU of 8he0 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (wild-type)
分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1
著者Matsuura, Y.
登録日2022-11-07
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
5UMZ
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BU of 5umz by Molmil
Structure of TNRC6A NLS in complex with importin-alpha
分子名称: GLYCEROL, Importin subunit alpha-1, TNRC6A
著者Chaston, J, Stewart, A.G, Christie, M.
登録日2017-01-30
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha.
PLoS ONE, 12, 2017
6WBA
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BU of 6wba by Molmil
Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBB
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BU of 6wbb by Molmil
Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者De Barros, A.C, Da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.663 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6WBC
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BU of 6wbc by Molmil
Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1
著者de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M.
登録日2020-03-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
5X8N
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BU of 5x8n by Molmil
Crystal structure of mouse importin-alpha1 bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein
分子名称: Epstein-Barr nuclear antigen leader protein, Importin subunit alpha-1
著者Nakada, R, Matsuura, Y.
登録日2017-03-03
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of importin-alpha bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein
Protein Sci., 26, 2017
7M60
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BU of 7m60 by Molmil
Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1
著者De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M.
登録日2021-03-25
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
3ZKV
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BU of 3zkv by Molmil
Importin13 cytosolic state
分子名称: CADMUS
著者Gruenwald, M, Lazzaretti, D, Bono, F.
登録日2013-01-24
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
3VE6
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BU of 3ve6 by Molmil
Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha
分子名称: Importin subunit alpha-2, Venezuelan equine encephalitis virus capsid protein NLS
著者Fan, F.
登録日2012-01-07
公開日2012-01-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.829 Å)
主引用文献Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha
To be Published
5OWU
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BU of 5owu by Molmil
Kap95:Nup1 complex
分子名称: Importin subunit beta-1, Nucleoporin NUP1
著者Stewart, M.
登録日2017-09-04
公開日2017-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p.
J. Mol. Biol., 349, 2005
2C1T
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BU of 2c1t by Molmil
Structure of the Kap60p:Nup2 complex
分子名称: IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2
著者Matsuura, Y, Stewart, M.
登録日2005-09-20
公開日2005-11-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nup50/Npap60 Function in Nuclear Import Complex Disassembly and Importin Recycling
Embo J., 24, 2005
5KLT
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BU of 5klt by Molmil
Prototypical P4[M]cNLS
分子名称: Importin subunit alpha-1, Prototypical P4[M]cNLS
著者Smith, K.M, Forwood, J.K.
登録日2016-06-25
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018

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