7LEQ

Structure of importin a2 bound to p50 NLS

Summary for 7LEQ

Entry DOI	10.2210/pdb7leq/pdb
Descriptor	Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit (3 entities in total)
Functional Keywords	nuclear import, importin alpha, nls, nf-kb, p50, protein transport
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	48176.17
Authors	Florio, T.J.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2021-01-14, release date: 2022-01-19, Last modification date: 2023-10-18)
Primary citation	Florio, T.J.,Lokareddy, R.K.,Yeggoni, D.P.,Sankhala, R.S.,Ott, C.A.,Gillilan, R.E.,Cingolani, G. Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13:1207-1207, 2022 Cited by PubMed: 35260573 DOI: 10.1038/s41467-022-28846-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.24 Å)

Structure validation