7M60

Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex

Summary for 7M60

• Entry DOI: 10.2210/pdb7m60/pdb
• Descriptor: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1 (3 entities in total)
• Functional Keywords: importin alpha, nuclear import, nls, mlh1, transport protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 52627.63

Authors

De Oliveira, H.C.,Da Silva, T.D.,Fukuda, C.A.,Fontes, M.R.M. (deposition date: 2021-03-25, release date: 2021-07-07, Last modification date: 2023-10-18)

• Primary citation: de Oliveira, H.C.,da Silva, T.D.,Salvador, G.H.M.,Moraes, I.R.,Fukuda, C.A.,de Barros, A.C.,Fontes, M.R.M.; Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.; Biochem.J., 478:2715-2732, 2021; PubMed: 34195786; DOI: 10.1042/BCJ20210401

Experimental method

X-RAY DIFFRACTION (2.3 Å)