6WBB

Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex

Summary for 6WBB

• Entry DOI: 10.2210/pdb6wbb/pdb
• Descriptor: Importin subunit alpha-1, DNA mismatch repair protein Mlh1 (3 entities in total)
• Functional Keywords: importin alpha, nls, nuclear import, mlh1, protein transport, protein transport-nuclear protein complex, protein transport/nuclear protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 52543.56

Authors

De Barros, A.C.,Da Silva, T.D.,Oliveira, H.C.,Fukuda, C.A.,Fontes, M.R.M. (deposition date: 2020-03-26, release date: 2021-07-07, Last modification date: 2023-10-18)

• Primary citation: de Oliveira, H.C.,da Silva, T.D.,Salvador, G.H.M.,Moraes, I.R.,Fukuda, C.A.,de Barros, A.C.,Fontes, M.R.M.; Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.; Biochem.J., 478:2715-2732, 2021; PubMed: 34195786; DOI: 10.1042/BCJ20210401

Experimental method

X-RAY DIFFRACTION (2.663 Å)