6NZ1
 
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6O0I
 | | NMR ensemble of computationally designed protein XAA | | Descriptor: | Design construct XAA | | Authors: | Wei, K.Y, Moschidi, D, Nerli, S, Sgourakis, N, Baker, D. | | Deposit date: | 2019-02-16 | | Release date: | 2020-04-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6NY8
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6NYE
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6NXM
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6NX2
 | | Crystal structure of computationally designed protein AAA | | Descriptor: | BROMIDE ION, Design construct AAA | | Authors: | Wei, K.Y, Bick, M.J. | | Deposit date: | 2019-02-07 | | Release date: | 2020-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6O0C
 | | NMR ensemble of computationally designed protein XAA_GVDQ mutant M4L | | Descriptor: | Design construct XAA_GVDQ mutant M4L | | Authors: | Wei, K.Y, Moschidi, D, Nerli, S, Sgourakis, N, Baker, D. | | Deposit date: | 2019-02-15 | | Release date: | 2020-04-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6NYI
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6NYK
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6NZ3
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3V50
 | | Complex of SHV S130G mutant beta-lactamase complexed to SA2-13 | | Descriptor: | (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, Beta-lactamase, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | | Authors: | Wei, K, van den Akker, F. | | Deposit date: | 2011-12-15 | | Release date: | 2012-08-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The importance of the trans-enamine intermediate as a beta-lactamase inhibition strategy probed in inhibitor-resistant SHV beta-lactamase variants.
Chemmedchem, 7, 2012
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7PER
 | | Model of the inner ring of the human nuclear pore complex | | Descriptor: | Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ... | | Authors: | Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. | | Deposit date: | 2021-08-11 | | Release date: | 2021-10-20 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
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7PEQ
 | | Model of the outer rings of the human nuclear pore complex | | Descriptor: | Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ... | | Authors: | Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. | | Deposit date: | 2021-08-11 | | Release date: | 2021-10-20 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
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3PEW
 | | S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2010-10-27 | | Release date: | 2011-03-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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3PEY
 | | S. cerevisiae Dbp5 bound to RNA and ADP BeF3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2010-10-27 | | Release date: | 2011-03-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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1XIP
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3GFP
 | | Structure of the C-terminal domain of the DEAD-box protein Dbp5 | | Descriptor: | DEAD box protein 5 | | Authors: | Erzberger, J.P, Dossani, Z.Y, Weirich, C.S, Weis, K, Berger, J.M. | | Deposit date: | 2009-02-27 | | Release date: | 2009-09-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the C-terminus of the mRNA export factor Dbp5 reveals the interaction surface for the ATPase activator Gle1
Proc.Natl.Acad.Sci.USA, 106, 2009
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3PEU
 | | S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 H337R and IP6 | | Descriptor: | ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2010-10-27 | | Release date: | 2011-03-23 | | Last modified: | 2020-10-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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3PEV
 | | S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 and IP6 | | Descriptor: | ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2010-10-27 | | Release date: | 2011-03-23 | | Last modified: | 2020-10-14 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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3RRN
 | | S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2011-04-29 | | Release date: | 2011-05-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.001 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
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3RRM
 | | S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | Deposit date: | 2011-04-29 | | Release date: | 2011-05-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
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1QGR
 | | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH) | | Descriptor: | PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) | | Authors: | Cingolani, G, Petosa, C, Weis, K, Muller, C.W. | | Deposit date: | 1999-05-04 | | Release date: | 1999-05-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
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1QGK
 | | STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA | | Descriptor: | PROTEIN (IMPORTIN ALPHA-2 SUBUNIT), PROTEIN (IMPORTIN BETA SUBUNIT) | | Authors: | Cingolani, G, Petosa, C, Weis, K, Muller, C.W. | | Deposit date: | 1999-04-29 | | Release date: | 1999-05-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
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6B85
 | | Crystal structure of transmembrane protein TMHC4_R | | Descriptor: | TMHC4_R | | Authors: | Lu, P, DiMaio, F, Min, D, Bowie, J, Wei, K.Y, Baker, D. | | Deposit date: | 2017-10-05 | | Release date: | 2018-03-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.889 Å) | | Cite: | Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
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6B87
 | | Crystal structure of transmembrane protein TMHC2_E | | Descriptor: | TMHC2_E | | Authors: | Lu, P, DiMaio, F, Min, D, Wei, K.Y, Bowie, J, Baker, D. | | Deposit date: | 2017-10-05 | | Release date: | 2018-03-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.947 Å) | | Cite: | Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
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