PDB: 160 件ウェブページステータス検索Chemie searchBIRD

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3SMB	Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF) 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ... 著者 Crichlow, G.V, Lolis, E.J. 登録日 2011-06-27 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates. Biochemistry, 51, 2012
3GAD	Structure of apomif 分子名称: ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION 著者 Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. 登録日 2009-02-17 公開日 2009-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
3T5S	Structure of macrophage migration inhibitory factor from Giardia lamblia 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-07-28 公開日 2011-08-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. J.Struct.Funct.Genom., 14, 2013
3DJH	Macrophage Migration Inhibitory Factor (MIF) at 1.25 A Resolution 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Crichlow, G.V, Lolis, E. 登録日 2008-06-23 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48, 2009
3GAC	Structure of mif with HPP 分子名称: 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ACETIC ACID, Macrophage migration inhibitory factor-like protein, ... 著者 Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. 登録日 2009-02-17 公開日 2009-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
3U18	Chicago Sky Blue 6B, A Novel Inhibitor for Macrophage Migration Inhibitory Factor 分子名称: 1,2-ETHANEDIOL, 6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid), GLYCEROL, ... 著者 Asojo, O.A. 登録日 2011-09-29 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF). J.Biol.Chem., 287, 2012
4XX7	Crystal structure of M2A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-01-29 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4Z1U	MIF in complex with 1-(4-methylphenyl)-3-phenylprop-2-yn-1-one 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-27 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
4GRU	crystallographic and biological characterization of N- and C- terminus mutants of human MIF 分子名称: 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, Macrophage migration inhibitory factor, ... 著者 Fan, C, Lolis, E. 登録日 2012-08-26 公開日 2013-09-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 crystallographic and biological characterization of N- and C- terminus mutants of human MIF To be Published
4GRQ	Characterization of N- and C- terminus mutants of human MIF 分子名称: 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor, ... 著者 Fan, C, Lolis, E. 登録日 2012-08-26 公開日 2013-10-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Characterization of N- and C- terminus mutants of human MIF To be Published
4GRO	Crystallographic and biological characterization of N- and C- terminus mutants of human MIF 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor 著者 Fan, C, Lolis, E. 登録日 2012-08-26 公開日 2013-10-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 crystallographic and biological characterization of N- and C- terminus mutants of human MIF To be Published
4GRN	crystal structure of PAAM mutant of human MIF 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SODIUM ION, ... 著者 Fan, C, Lolis, E, Rajesekaran, D. 登録日 2012-08-26 公開日 2013-09-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 crystallographic and biological chacerterization of N- and C-terminus of MIF To be Published
4GRP	Crystallographic and biological characterization of N- and C- terminus mutants of human MIF 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION 著者 Fan, C, Lolis, E. 登録日 2012-08-26 公開日 2013-10-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Crystallographic and biological characterization of N- and C- terminus mutants of human MIF To be Published
4Z15	MIF in complex with 3-(2-furylmethyl)-2-thioxo-1,3-thiazolan-4-one 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-26 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
4Z1T	MIF in complex with 4-[(4-oxo-2-thioxo-1,3-thiazolan-3-yl)methyl]benzonitrile 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-27 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
5BS9	Crystal structure of N109A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-06-01 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4GRR	characterization of N- and C- terminus mutants of human MIF 分子名称: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor, ... 著者 Fan, C, Lolis, E. 登録日 2012-08-26 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Characterization of N- and C- terminus mutants of human MIF To be Published
4GUM	Cystal structure of locked-trimer of human MIF 分子名称: CHLORIDE ION, Macrophage migration inhibitory factor 著者 Fan, C, Lolis, E. 登録日 2012-08-29 公開日 2013-07-03 最終更新日 2020-11-18 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations. Proc.Natl.Acad.Sci.USA, 110, 2013
5B4O	Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14 分子名称: 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ... 著者 Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N. 登録日 2016-04-07 公開日 2016-04-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression Chem. Biol., 17, 2010
5BSJ	Crystal structure of S63A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-06-02 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of S63A mutant of human macrophage migration inhibitory factor To Be Published
3IJJ	Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer) 分子名称: (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ... 著者 Crichlow, G.V, Cho, Y, Lolis, E.J. 登録日 2009-08-04 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
3IJG	Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013 分子名称: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor 著者 Crichlow, G.V, Cho, Y, Lolis, E.J. 登録日 2009-08-04 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
3KAN	D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP 分子名称: 4-phenylpyrimidine, CHLORIDE ION, D-dopachrome tautomerase 著者 Zierow, S, Lolis, E. 登録日 2009-10-19 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment. Faseb J., 28, 2014
3JSF	Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 638 at 1.93a resolution 分子名称: 7-(2-fluorobenzyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION 著者 Mclean, L, Zhang, Y. 登録日 2009-09-10 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening. Bioorg.Med.Chem.Lett., 19, 2009
3HOF	Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution 分子名称: CAFFEIC ACID, Macrophage migration inhibitory factor 著者 Crawley, L, Barker, J, Cheng, R.K.Y, Wood, M, Felicetti, B. 登録日 2009-06-02 公開日 2009-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution To be Published

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