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3KAN

D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP

Summary for 3KAN
Entry DOI10.2210/pdb3kan/pdb
Related1DPT 3B64 3B9S 3KER
DescriptorD-dopachrome tautomerase, 4-phenylpyrimidine, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsimmune response, cytokine, tautomerase, cytokine-inhibitor complex, cytokine/inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total formula weight38320.04
Authors
Zierow, S.,Lolis, E. (deposition date: 2009-10-19, release date: 2011-04-20, Last modification date: 2023-09-06)
Primary citationRajasekaran, D.,Zierow, S.,Syed, M.,Bucala, R.,Bhandari, V.,Lolis, E.J.
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.
Faseb J., 28:4961-4971, 2014
Cited by
PubMed: 25016026
DOI: 10.1096/fj.14-256636
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.13 Å)
Structure validation

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