4GUM
Cystal structure of locked-trimer of human MIF
Summary for 4GUM
Entry DOI | 10.2210/pdb4gum/pdb |
Descriptor | Macrophage migration inhibitory factor, CHLORIDE ION (3 entities in total) |
Functional Keywords | alpha/beta mixture, cytokine and isomerase, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 9 |
Total formula weight | 111380.49 |
Authors | |
Primary citation | Fan, C.,Rajasekaran, D.,Syed, M.A.,Leng, L.,Loria, J.P.,Bhandari, V.,Bucala, R.,Lolis, E.J. MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations. Proc.Natl.Acad.Sci.USA, 110:10994-10999, 2013 Cited by PubMed: 23776208DOI: 10.1073/pnas.1221817110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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