4GUM
Cystal structure of locked-trimer of human MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Macrophage migration inhibitory factor | polymer | 114 | 12344.1 | 9 | UniProt (P14174) Pfam (PF01187) UniProt (by SIFTS) (Q6DN04) In PDB | Homo sapiens (Human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | A, C, D, E, I | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 3 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I: 1 - 114 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Cys 110 | Asn 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 111096.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 283.6 | |
| All* | Total formula weight | 111380.5 |
