4XX7
Crystal structure of M2A mutant of human macrophage migration inhibitory factor
Summary for 4XX7
Entry DOI | 10.2210/pdb4xx7/pdb |
Related | 4GRN 4GRO 4P01 4P0H 4PKZ 4PLU 4TRF 4TRU 4XX8 5BS9 5BSC 5BSI |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (5 entities in total) |
Functional Keywords | isomerase, surface, mutation |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P14174 |
Total number of polymer chains | 3 |
Total formula weight | 37385.29 |
Authors | Pantouris, G.,Lolis, E. (deposition date: 2015-01-29, release date: 2015-09-30, Last modification date: 2023-09-27) |
Primary citation | Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22:1197-1205, 2015 Cited by PubMed: 26364929DOI: 10.1016/j.chembiol.2015.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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