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5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
著者Miller, D.J, Schulman, B.A.
登録日2016-12-27
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
5HKX
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BU of 5hkx by Molmil
Crystal Structure of c-Cbl TKBD-RING domains (Y371E mutant) Refined to 1.85 A Resolution
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase CBL, SODIUM ION, ...
著者Lovell, S, Battaile, K.P, Mehzabeen, N, Zhang, N, Cooper, A, Gao, P, Perez, R.P.
登録日2016-01-14
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of c-Cbl TKBD-RING domains (Y371E mutant) Refined to 1.85 A Resolution
To be published
5TRB
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BU of 5trb by Molmil
Crystal structure of the RNF20 RING domain
分子名称: E3 ubiquitin-protein ligase BRE1A, ZINC ION
著者Foglizzo, M, Middleton, A.J, Day, C.L.
登録日2016-10-25
公開日2016-11-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.
J.Mol.Biol., 428, 2016
5J3X
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BU of 5j3x by Molmil
Structure of c-CBL Y371F
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, ZINC ION
著者Huang, D.T, Buetow, L, Dou, H.
登録日2016-03-31
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Bmc Biol., 14, 2016
3JBY
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BU of 3jby by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (C2 symmetry)
分子名称: '-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', CALCIUM ION, ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-22
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBX
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BU of 3jbx by Molmil
Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry)
分子名称: 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', 5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3', 5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3', ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-22
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBW
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BU of 3jbw by Molmil
Cryo-electron microscopy structure of RAG Paired Complex (with NBD, no symmetry)
分子名称: 12-RSS signal end forward strand, 5'-D(P*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3', Nicked 12-RSS intermediate reverse strand, ...
著者Ru, H, Chambers, M.G, Fu, T.-M, Tong, A.B, Liao, M, Wu, H.
登録日2015-10-21
公開日2015-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
4R7E
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BU of 4r7e by Molmil
Structure of Bre1 RING domain
分子名称: E3 ubiquitin-protein ligase BRE1, ZINC ION
著者Kumar, P, Wolberger, C.
登録日2014-08-27
公開日2015-05-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Structure of the yeast Bre1 RING domain.
Proteins, 83, 2015
2MWX
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BU of 2mwx by Molmil
The RING Domain of human Promyelocytic Leukemia Protein (PML)
分子名称: Protein PML, ZINC ION
著者Huang, S.Y, Chang, C.F, Fan, P.J, Guntert, P, Shih, H.M, Huang, T.H.
登録日2014-12-02
公開日2015-02-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The RING domain of human promyelocytic leukemia protein (PML).
J.Biomol.Nmr, 61, 2015
4GB0
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BU of 4gb0 by Molmil
Crystal Structure of the RING domain of RNF168
分子名称: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
著者Zhang, X.Q, Wang, C.L, Zang, J.Y.
登録日2012-07-26
公開日2013-07-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for role of ring finger protein RNF168 RING domain
Cell Cycle, 12, 2013
3ZNI
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BU of 3zni by Molmil
Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ...
著者Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T.
登録日2013-02-14
公開日2013-07-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3.
Nat.Struct.Mol.Biol., 20, 2013
4KBL
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BU of 4kbl by Molmil
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2013-04-23
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
4KC9
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BU of 4kc9 by Molmil
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2013-04-24
公開日2013-05-29
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (3.603 Å)
主引用文献Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
4A4B
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BU of 4a4b by Molmil
Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
著者Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
登録日2011-10-08
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4A4C
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BU of 4a4c by Molmil
Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
著者Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
登録日2011-10-08
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4A49
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BU of 4a49 by Molmil
Structure of phosphoTyr371-c-Cbl-UbcH5B complex
分子名称: E3 ubiquitin-protein ligase CBL, POTASSIUM ION, Ubiquitin-conjugating enzyme E2 D2, ...
著者Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
登録日2011-10-07
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.214 Å)
主引用文献Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.
Nat. Struct. Mol. Biol., 19, 2012
2Y1N
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BU of 2y1n by Molmil
Structure of c-Cbl-ZAP-70 peptide complex
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, ...
著者Dou, H, Sibbet, G.J, Huang, D.T.
登録日2010-12-08
公開日2012-01-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
2Y1M
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BU of 2y1m by Molmil
Structure of native c-Cbl
分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION
著者Dou, H, Sibbet, G.J, Huang, D.T.
登録日2010-12-08
公開日2012-01-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
2LDR
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BU of 2ldr by Molmil
Solution structure of Helix-RING domain of Cbl-b in the Tyr363 phosphorylated form
分子名称: E3 ubiquitin-protein ligase CBL-B, ZINC ION
著者Kumeta, H, Kobashigawa, Y, Inagaki, F.
登録日2011-06-01
公開日2011-12-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b
Proc.Natl.Acad.Sci.USA, 108, 2011
3VGO
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BU of 3vgo by Molmil
Crystal structure of the N-terminal fragment of Cbl-b
分子名称: E3 ubiquitin-protein ligase CBL-B
著者Kobashigawa, Y, Noda, N.N, Inagaki, F.
登録日2011-08-18
公開日2011-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b
Proc.Natl.Acad.Sci.USA, 108, 2011
3L11
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BU of 3l11 by Molmil
Crystal Structure of the Ring Domain of RNF168
分子名称: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
著者Neculai, D, Yermekbayeva, L, Crombet, L, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-12-10
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
3KNV
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BU of 3knv by Molmil
Crystal structure of the RING and first zinc finger domains of TRAF2
分子名称: TNF receptor-associated factor 2, ZINC ION
著者Yin, Q, Wu, H.
登録日2009-11-12
公開日2009-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the lack of E2 interaction in the RING domain of TRAF2.
Biochemistry, 48, 2009
2K4D
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BU of 2k4d by Molmil
E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity
分子名称: E3 ubiquitin-protein ligase CBL, ZINC ION
著者Huang, A, De Jong, R.N, Wienk, H, Winkler, S.G, Timmers, H.T.M, Boelens, R.
登録日2008-06-06
公開日2009-01-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity
J.Mol.Biol., 385, 2009
2ECW
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BU of 2ecw by Molmil
Solution structure of the Zinc finger, C3HC4 type (RING finger) domain Tripartite motif protein 30
分子名称: Tripartite motif-containing protein 30, ZINC ION
著者Abe, H, Miyamoto, K, Tochio, N, Yoneyama, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-14
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Zinc finger, C3HC4 type (RING finger) domain Tripartite motif protein 30
To be Published
1JM7
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BU of 1jm7 by Molmil
Solution structure of the BRCA1/BARD1 RING-domain heterodimer
分子名称: BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION
著者Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E.
登録日2001-07-17
公開日2001-10-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001

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