4KBL

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism

Summary for 4KBL

• Entry DOI: 10.2210/pdb4kbl/pdb
• Related: 4KC9
• Descriptor: E3 ubiquitin-protein ligase ARIH1, ZINC ION (2 entities in total)
• Functional Keywords: ring-ibr-ring, e3 ubiquitin ligase, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q9Y4X5
• Total number of polymer chains: 2
• Total formula weight: 129468.71

Authors

Duda, D.M.,Olszewski, J.L.,Schulman, B.A. (deposition date: 2013-04-23, release date: 2013-05-29, Last modification date: 2024-02-28)

• Primary citation: Duda, D.M.,Olszewski, J.L.,Schuermann, J.P.,Kurinov, I.,Miller, D.J.,Nourse, A.,Alpi, A.F.,Schulman, B.A.; Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.; Structure, 21:1030-1041, 2013; PubMed: 23707686; DOI: 10.1016/j.str.2013.04.019

Experimental method

X-RAY DIFFRACTION (3.3 Å)