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4KBL

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BE3 ubiquitin-protein ligase ARIH1polymer55964341.92UniProt (Q9Y4X5)
Pfam (PF21235)
Pfam (PF00097)
Pfam (PF01485)
Pfam (PF22191)
Pfam (PF19422)
In PDB
Homo sapiens (human)H7-AP2, HHARI, Monocyte protein 6, MOP-6, Protein ariadne-1 homolog, ARI-1, UbcH7-binding protein, UbcM4-interacting protein, Ubiquitin-conjugating enzyme E2-binding protein 1
2A, BZINC IONnon-polymer65.412Chemie (ZN)
Sequence modifications
A, B: 1 - 557 (UniProt: Q9Y4X5)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight128683.8
Non-Polymers*Number of molecules12
Total formula weight784.9
All*Total formula weight129468.7
*Water molecules are not included.

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PDB entries from 2024-07-17

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