4KBL
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase ARIH1 | polymer | 559 | 64341.9 | 2 | UniProt (Q9Y4X5) Pfam (PF21235) Pfam (PF00097) Pfam (PF01485) Pfam (PF22191) Pfam (PF19422) | Homo sapiens (human) | H7-AP2, HHARI, Monocyte protein 6, MOP-6, Protein ariadne-1 homolog, ARI-1, UbcH7-binding protein, UbcM4-interacting protein, Ubiquitin-conjugating enzyme E2-binding protein 1 |
| 2 | C, D, E, F, G... (A, B) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 557 (UniProt: Q9Y4X5)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128683.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 784.9 | |
| All* | Total formula weight | 129468.7 |
