Structure of c-CBL Y371F

Summary for 5J3X

DescriptorE3 ubiquitin-protein ligase CBL, ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywordsubiquitin ligase, ring e3, ligase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P22681
Total number of polymer chains6
Total molecular weight271366.32
Huang, D.T.,Buetow, L.,Dou, H. (deposition date: 2016-03-31, release date: 2016-09-21)
Primary citation
Buetow, L.,Tria, G.,Ahmed, S.F.,Hock, A.,Dou, H.,Sibbet, G.J.,Svergun, D.I.,Huang, D.T.
Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Bmc Biol., 14:76-76, 2016
PubMed: 27609087 (PDB entries with the same primary citation)
DOI: 10.1186/s12915-016-0298-6
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.256300.5%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload