5J3X
Structure of c-CBL Y371F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | E3 ubiquitin-protein ligase CBL | polymer | 391 | 45056.8 | 6 | UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) Pfam (PF00097) | Homo sapiens (Human) | Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,Signal transduction protein CBL |
| 2 | G, H, J, K, M... (A, B, C, D, E...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | I, L, O, R, U... (A, B, C, D, E...) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 47 - 435 (UniProt: P22681)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | expression tag |
| Ser 46 | - | expression tag |
| Phe 371 | Tyr 371 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 270340.9 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1025.4 | |
| All* | Total formula weight | 271366.3 |
