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5J3X

Structure of c-CBL Y371F

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...E3 ubiquitin-protein ligase CBLpolymer39145056.86UniProt (P22681)
Pfam (PF02262)
Pfam (PF02761)
Pfam (PF02762)
Pfam (PF00097)
In PDB
Homo sapiens (Human)Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,Signal transduction protein CBL
2A, B, C, D, E...ZINC IONnon-polymer65.412Chemie (ZN)
3A, B, C, D, E...CALCIUM IONnon-polymer40.16Chemie (CA)
4waterwater18.094Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 47 - 435 (UniProt: P22681)
PDBExternal DatabaseDetails
Gly 45-expression tag
Ser 46-expression tag
Phe 371Tyr 371engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight270340.9
Non-Polymers*Number of molecules18
Total formula weight1025.4
All*Total formula weight271366.3
*Water molecules are not included.

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PDB entries from 2024-09-18

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