3L11
Crystal Structure of the Ring Domain of RNF168
Summary for 3L11
Entry DOI | 10.2210/pdb3l11/pdb |
Descriptor | E3 ubiquitin-protein ligase RNF168, ZINC ION, MALONATE ION, ... (4 entities in total) |
Functional Keywords | e3 ligase, ring domain, dna damage, chromatin regulator, chromosomal protein, dna repair, ligase, metal-binding, nucleus, phosphoprotein, ubl conjugation pathway, zinc-finger, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q8IYW5 |
Total number of polymer chains | 1 |
Total formula weight | 13466.16 |
Authors | Neculai, D.,Yermekbayeva, L.,Crombet, L.,Weigelt, J.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-12-10, release date: 2010-01-19, Last modification date: 2023-09-06) |
Primary citation | Campbell, S.J.,Edwards, R.A.,Leung, C.C.,Neculai, D.,Hodge, C.D.,Dhe-Paganon, S.,Glover, J.N. Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. J.Biol.Chem., 287:23900-23910, 2012 Cited by PubMed: 22589545DOI: 10.1074/jbc.M112.359653 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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