PDB: 8880 件ウェブページステータス検索Chemie searchBIRD

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7KOP	The crystal structure of the 2009/H1N1/California PA endonuclease I38T mutant in complex with SJ000988539 分子名称: 2-(2-fluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Seetharaman, J, White, S.W. 登録日 2020-11-09 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 The crystal structure of the 2009/H1N1/California PA endonuclease I38T mutant in complex with SJ000988539 To Be Published
4J04	Crystal structure of hcv ns5b polymerase in complex with 4-CHLORO-2-{[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID 分子名称: 4-chloro-2-{[(2,4,5-trichlorophenyl)sulfonyl]amino}benzoic acid, Genome polyprotein, MANGANESE (II) ION 著者 Coulombe, R. 登録日 2013-01-30 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
8E1Q	The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 分子名称: 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-08-11 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044 To Be Published
8E21	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034 分子名称: 5-hydroxy-6-oxo-N-[2-(pyridin-4-yl)ethyl]-2-{[2-(trifluoromethyl)phenyl]methyl}-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2022-08-12 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034 To Be Published
7LP8	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 分子名称: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W. 登録日 2021-02-11 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 To Be Published
7LP7	The crystal structure of the wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 分子名称: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W. 登録日 2021-02-11 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 To Be Published
8EDZ	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319 分子名称: Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Cuypers, M.G, Slavish, J.P, Jayaraman, S, Rankovic, Z, White, S.W. 登録日 2022-09-06 公開日 2022-10-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319 To Be Published
4AVG	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 2 分子名称: (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-05-25 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
4H61	Structure of the Schizosaccharomyces pombe Mediator subunit Med6 分子名称: Mediator of RNA polymerase II transcription subunit 6 著者 Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. 登録日 2012-09-19 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the Mediator head module. Nature, 492, 2012
7XW2	Cryo-EM structure of human DICER-pre-miRNA in a dicing state 分子名称: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER) 著者 Lee, H, Roh, S.-H. 登録日 2022-05-26 公開日 2023-03-08 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structure of the human DICER-pre-miRNA complex in a dicing state. Nature, 615, 2023
4AWF	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with 2 4-dioxo-4-phenylbutanoic acid DPBA 分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, POLYMERASE PA 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-06-03 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
4AVQ	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease 分子名称: MAGNESIUM ION, MANGANESE (II) ION, POLYMERASE PA 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-05-29 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
4AWH	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with rUMP 分子名称: MANGANESE (II) ION, POLYMERASE PA, URIDINE-5'-MONOPHOSPHATE 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-06-03 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
4AVL	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP 分子名称: MANGANESE (II) ION, POLYMERASE PA, THYMIDINE-5'-PHOSPHATE 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H.J, Ruigrok, R.W.H, Cusack, S. 登録日 2012-05-28 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
3J7O	Structure of the mammalian 60S ribosomal subunit 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. 登録日 2014-08-01 公開日 2014-09-03 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
2ZVK	Crystal structure of PCNA in complex with DNA polymerase eta fragment 分子名称: DNA polymerase eta, Proliferating cell nuclear antigen 著者 Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. 登録日 2008-11-11 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
4AWG	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3 分子名称: (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA, ... 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-06-03 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
2ZVL	Crystal structure of PCNA in complex with DNA polymerase kappa fragment 分子名称: DNA polymerase kappa, Proliferating cell nuclear antigen, SULFATE ION, ... 著者 Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. 登録日 2008-11-11 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
2ZVM	Crystal structure of PCNA in complex with DNA polymerase iota fragment 分子名称: DNA polymerase iota, Proliferating cell nuclear antigen 著者 Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M. 登録日 2008-11-11 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen J.Biol.Chem., 284, 2009
3K59	Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K58	Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex 分子名称: DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K5L	Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3K57	Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
6IC9	Crystal structure of the SPOC domain of human PHF3 in complex with RNA polymerase II CTD diheptapeptide phosphorylated on Ser2Ser7 分子名称: PHD finger protein 3, TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO 著者 Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. 登録日 2018-12-03 公開日 2020-07-15 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.748 Å) 主引用文献 PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC Nat Commun, 12, 2021
3MMY	Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclear pore complex protein Nup98, mRNA export factor 著者 Hoelz, A, Ren, Y. 登録日 2010-04-20 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proc.Natl.Acad.Sci.USA, 107, 2010

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