8EDZ
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319
Summary for 8EDZ
Entry DOI | 10.2210/pdb8edz/pdb |
Descriptor | Polymerase acidic protein, benzyl [2-(6-{[2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl]carbamoyl}-5-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)propan-2-yl]carbamate, Hexa Vinylpyrrolidone K15, ... (6 entities in total) |
Functional Keywords | nuclease, influenza, inhibitor resistance, viral protein |
Biological source | Influenza A virus (A/Luxembourg/43/2009(H1N1)) More |
Total number of polymer chains | 1 |
Total formula weight | 24517.61 |
Authors | Cuypers, M.G.,Slavish, J.P.,Jayaraman, S.,Rankovic, Z.,White, S.W. (deposition date: 2022-09-06, release date: 2022-10-05, Last modification date: 2023-10-18) |
Primary citation | Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W. The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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