2ZVM

Crystal structure of PCNA in complex with DNA polymerase iota fragment

Summary for 2ZVM

• Entry DOI: 10.2210/pdb2zvm/pdb
• Related: 2ZVK 2ZVL
• Descriptor: Proliferating cell nuclear antigen, DNA polymerase iota (3 entities in total)
• Functional Keywords: dna replication, pcna, clamp, translesion synthesis, tls, dna polymerase, complex, pip-box, dna polymerase iota, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P12004
• Total number of polymer chains: 6
• Total formula weight: 94028.13

Authors

Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M. (deposition date: 2008-11-11, release date: 2009-02-10, Last modification date: 2023-11-01)

• Primary citation: Hishiki, A.,Hashimoto, H.,Hanafusa, T.,Kamei, K.,Ohashi, E.,Shimizu, T.,Ohmori, H.,Sato, M.; Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen; J.Biol.Chem., 284:10552-10560, 2009; PubMed: 19208623; DOI: 10.1074/jbc.M809745200

Experimental method

X-RAY DIFFRACTION (2.3 Å)