7KOP

The crystal structure of the 2009/H1N1/California PA endonuclease I38T mutant in complex with SJ000988539

Summary for 7KOP

• Entry DOI: 10.2210/pdb7kop/pdb
• Related: 7K87
• Descriptor: Protein PA-X, MANGANESE (II) ION, 2-(2-fluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-1,6-dihydropyrimidine-4-carboxamide, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein, hydrolase
• Biological source: Influenza A virus; More
• Total number of polymer chains: 1
• Total formula weight: 24395.45

Authors

Cuypers, M.G.,Slavish, P.J.,Seetharaman, J.,White, S.W. (deposition date: 2020-11-09, release date: 2021-11-10, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, P.J.,Seetharaman, J.,White, S.W.; The crystal structure of the 2009/H1N1/California PA endonuclease I38T mutant in complex with SJ000988539; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)