7LP8

The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476

Summary for 7LP8

• Entry DOI: 10.2210/pdb7lp8/pdb
• Descriptor: Polymerase acidic protein, (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein
• Biological source: Influenza A virus (A/Luxembourg/43/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 24474.58

Authors

Cuypers, M.G.,Slavish, P.J.,Rankovic, Z.,White, S.W. (deposition date: 2021-02-11, release date: 2022-02-16, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, P.J.,Rankovic, Z.,White, S.W.; The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.55 Å)