7LP8
The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polymerase acidic protein | polymer | 197 | 23136.3 | 1 | UniProt (C6H0Y9) Pfam (PF00603) In PDB | Influenza A virus (A/Luxembourg/43/2009(H1N1)) | |
2 | A | (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate | non-polymer | 463.5 | 1 | Chemie (YAD) | |||
3 | A | Hexa Vinylpyrrolidone K15 | non-polymer | 668.9 | 1 | Chemie (QQ4) | |||
4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: C6H0Y9)
A: 73 - 196 (UniProt: C6H0Y9)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Thr 38 | Ile 38 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 51 | - | linker |
Gly 52 | - | linker |
Ser 53 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23136.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1338.3 | |
All* | Total formula weight | 24474.6 |