8E1Q

The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044

Summary for 8E1Q

• Entry DOI: 10.2210/pdb8e1q/pdb
• Descriptor: Polymerase acidic protein, MANGANESE (II) ION, 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyrimidine-4-carboxamide, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein
• Biological source: Influenza A virus (A/Luxembourg/43/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 24570.56

Authors

Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W. (deposition date: 2022-08-11, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W.; The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)