7Q63
| The tandem SH2 domains of SYK | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | 登録日 | 2021-11-05 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The tandem SH2 domains of SYK To Be Published
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7Q5W
| The tandem SH2 domains of SYK with a bound TYROBP diphospho-ITAM peptide | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | 登録日 | 2021-11-04 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The tandem SH2 domains of SYK To Be Published
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8SPE
| Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P31 | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2023-05-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8P7B
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7Q5T
| The tandem SH2 domains of SYK with a bound FCER1G diphospho-ITAM peptide | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, High affinity immunoglobulin epsilon receptor subunit gamma, ... | 著者 | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | 登録日 | 2021-11-04 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The tandem SH2 domains of SYK To Be Published
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7QCQ
| VHH Z70 in interaction with PHF6 Tau peptide | 分子名称: | GLYCEROL, Tau 301-312, VHH Z70 | 著者 | Danis, C, Dupre, E, Zejneli, O, Caillierez, R, Arrial, A, Begard, S, Loyens, A, Mortelecque, J, Cantrelle, F.-X, Hanoulle, X, Rain, J.-C, Colin, M, Buee, L, Landrieu, I. | 登録日 | 2021-11-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment. Mol.Ther., 30, 2022
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8SPZ
| Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with dioctanoyl phosphatidylserine | 分子名称: | Apoptosis regulator BAX, SULFATE ION | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E, Miller, M.S. | 登録日 | 2023-05-04 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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7TD6
| aRML prion fibril | 分子名称: | Major prion protein | 著者 | Hoyt, F, Standke, H.G, Artikis, E, Caughey, B, Kraus, A. | 登録日 | 2021-12-30 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains. Nat Commun, 13, 2022
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8SVK
| Crystal structure of Bax D71N core domain BH3-groove dimer | 分子名称: | Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Miller, M.S, Czabotar, P.E, Colman, P.M. | 登録日 | 2023-05-16 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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7Q5U
| The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | 登録日 | 2021-11-04 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The tandem SH2 domains of SYK To Be Published
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8PHV
| Structure of Human selenomethionylated Cdc123 bound to domain 3 of eIF2 gamma | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3 | 著者 | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | 登録日 | 2023-06-20 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Binding of human Cdc123 to eIF2 gamma. J.Struct.Biol., 215, 2023
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8PEO
| H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | 著者 | Koutna, E, Kouba, T, Veverka, V. | 登録日 | 2023-06-14 | 公開日 | 2023-08-16 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
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8PC5
| H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | 著者 | Koutna, E, Kouba, T, Veverka, V. | 登録日 | 2023-06-09 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
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8SRX
| Crystal structure of BAK-BAX heterodimer with lysoPC | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BAX, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S. | 登録日 | 2023-05-07 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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5I66
| X-ray structure of the Fab fragment of 8B6, a murine monoclonal antibody specific for the human serotonin transporter | 分子名称: | 8B6 antibody, heavy chain, light chain | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.624 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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7QHG
| LIM domain kinase 2 (LIMK2) in complex with TH-470 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-methylpropanoylamino)-~{N}-[2-[(phenylmethyl)-[4-(phenylsulfamoyl)phenyl]carbonyl-amino]ethyl]-1,3-thiazole-5-carboxamide, LIM domain kinase 2 | 著者 | Mathea, S, Salah, E, Hanke, T, Knapp, S. | 登録日 | 2021-12-12 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J.Med.Chem., 65, 2022
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8PHD
| Structure of Human Cdc123 bound to domain 3 of eIF2 gamma and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3, ... | 著者 | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | 登録日 | 2023-06-19 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Binding of human Cdc123 to eIF2 gamma. J.Struct.Biol., 215, 2023
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8SRY
| Crystal structure of BAK-BAX heterodimer with C12E8 | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, ... | 著者 | Brouwer, J.M, Czabotar, P.E, Colman, P.M, Miller, M.S. | 登録日 | 2023-05-08 | 公開日 | 2023-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids. Febs J., 291, 2024
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8PC6
| H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | 著者 | Koutna, E, Kouba, T, Veverka, V. | 登録日 | 2023-06-09 | 公開日 | 2023-08-16 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
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5LBD
| Crystal structure of the N-domain of HMA6, a copper-transporting P-type ATPase | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ... | 著者 | Mayerhofer, H, Ravaud, S, Pebay-Peyroula, E. | 登録日 | 2016-06-15 | 公開日 | 2017-08-02 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insights into the Nucleotide-Binding Domains of the P1B-type ATPases HMA6 and HMA8 from Arabidopsis thaliana. PLoS ONE, 11, 2016
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6WTK
| Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication | 分子名称: | 3C-like proteinase, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | 著者 | Khan, M.B, Arutyunova, E, Young, H.S, Lemieux, M.J. | 登録日 | 2020-05-03 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun, 11, 2020
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5I75
| X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site | 分子名称: | (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coleman, J.A, Green, E.M, Gouaux, E. | 登録日 | 2016-02-16 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | X-ray structures and mechanism of the human serotonin transporter. Nature, 532, 2016
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7SUS
| Crystal structure of Apelin receptor in complex with small molecule | 分子名称: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apelin receptor, ... | 著者 | Xu, F, Yue, Y, Liu, L.E, Han, G.W, Hanson, M. | 登録日 | 2021-11-18 | 公開日 | 2022-07-27 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insight into apelin receptor-G protein stoichiometry. Nat.Struct.Mol.Biol., 29, 2022
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6YRF
| Vip3Bc1 tetramer | 分子名称: | Vegetative insecticidal protein | 著者 | Thompson, R.F, Byrne, M.J, Iadanza, M.I, Arribas Perez, M, Maskell, D.P, George, R.M, Hesketh, E.L, Beales, P.A, Zack, M.D, Berry, C. | 登録日 | 2020-04-20 | 公開日 | 2021-03-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane. Nat Commun, 12, 2021
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6AVB
| CryoEM structure of Mical Oxidized Actin (Class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | 著者 | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | 登録日 | 2017-09-01 | 公開日 | 2018-01-17 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
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