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8PC5

H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex

Replaces:  7PGV
Summary for 8PC5
Entry DOI10.2210/pdb8pc5/pdb
EMDB information17594
DescriptorWidom 601 DNA (147-MER), Histone H3, Histone H4, ... (7 entities in total)
Functional Keywordsnucleosome, transcription elongation, methylation, complex, dna binding protein, transcription
Biological sourcesynthetic construct
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Total number of polymer chains11
Total formula weight259169.68
Authors
Koutna, E.,Kouba, T.,Veverka, V. (deposition date: 2023-06-09, release date: 2023-08-16, Last modification date: 2023-11-15)
Primary citationKoutna, E.,Lux, V.,Kouba, T.,Skerlova, J.,Novacek, J.,Srb, P.,Hexnerova, R.,Svachova, H.,Kukacka, Z.,Novak, P.,Fabry, M.,Poepsel, S.,Veverka, V.
Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51:10011-10025, 2023
Cited by
PubMed: 37615563
DOI: 10.1093/nar/gkad674
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.02 Å)
Structure validation

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