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8PC5

H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex

Replaces:  7PGV
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1IWidom 601 DNA (147-MER)polymer14745138.81synthetic construct
2A, EHistone H3polymer13515332.02UniProt (A0A310TTQ1)
Pfam (PF00125)
UniProt (by SIFTS) (P84233)
In PDB
Xenopus laevis (African clawed frog)
3B, FHistone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
In PDB
Xenopus laevis (African clawed frog)
4C, GHistone H2Apolymer12913978.22UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
In PDB
Xenopus laevis (African clawed frog)
5D, HHistone H2B 1.1polymer12213524.82UniProt (P02281)
Pfam (PF00125)
In PDB
Xenopus laevis (African clawed frog)H2B1.1
6KPC4 and SFRS1-interacting proteinpolymer53060224.51UniProt (O75475)
Pfam (PF00855)
Pfam (PF11467)
In PDB
Homo sapiens (human)CLL-associated antigen KW-7,Dense fine speckles 70 kDa protein,DFS 70,Lens epithelium-derived growth factor,Transcriptional coactivator p75/p52
7JWidom 601 DNA (147-MER)polymer14745610.01synthetic construct
Sequence modifications
A, E: 1 - 135 (UniProt: A0A310TTQ1)
PDBExternal DatabaseDetails
Ala 110Cys 111conflict
D, H: 1 - 122 (UniProt: P02281)
PDBExternal DatabaseDetails
Thr 29Ser 33conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight259169.7
All*Total formula weight259169.7
*Water molecules are not included.

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PDB entries from 2024-07-31

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