PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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4QXG	Antigen binding fragment of an anti IFNAR1 antibody 分子名称: Fab, heavy chain, IgG1, ... 著者 Oganesyan, V.Y, Dall'Acqua, W.F. 登録日 2014-07-20 公開日 2015-02-25 最終更新日 2015-04-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-alpha receptor 1 antibody. MAbs, 7, 2015
6IW0	Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state 分子名称: Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A 著者 Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. 登録日 2018-12-04 公開日 2019-02-13 最終更新日 2019-02-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26, 2019
5D70	Crystal structure of MOR03929, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, heavy chain, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-13 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
5D7S	Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment 分子名称: (2S,3S)-butane-2,3-diol, Immunglobulin G1 Fab fragment, heavy chain, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-14 公開日 2015-10-14 最終更新日 2016-01-13 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
5D72	Crystal structure of MOR04252, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: DI(HYDROXYETHYL)ETHER, Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-13 公開日 2015-10-14 最終更新日 2016-01-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
3X3G	Fab fragment from anti TRAIL-R2 Human Agonist Antibody KMTR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of KMTR2, ... 著者 Tamada, T. 登録日 2015-01-20 公開日 2015-12-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2 Sci Rep, 5, 2015
3X3F	TRAIL-R2 Extracellular Region Complexed to a Fab fragment from Human Agonist Antibody KMTR2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... 著者 Tamada, T. 登録日 2015-01-20 公開日 2015-12-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2 Sci Rep, 5, 2015
8IA6	Crystal structure of scFv antibody against Phospholipase A2 of Echis carinatus venom 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, scFv antibody 著者 Kumar, A, Madni, Z.K, Salunke, D.M. 登録日 2023-02-07 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of scFv antibody against Phospholipase A2 of Echis carinatus venom To Be Published
6J71	HuA21-scFv in complex with the extracellular domain(ECD) of HER2 分子名称: Receptor tyrosine-protein kinase erbB-2, anti-HER2 humanized antibody HuA21, beta-D-mannopyranose, ... 著者 Wang, Z, Guo, G, Cheng, B, Zhu, Z, Niu, L, Zhang, H. 登録日 2019-01-16 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.918 Å) 主引用文献 Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells. Acta Crystallogr D Struct Biol, 75, 2019
4QXU	Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody 分子名称: Matrix metalloproteinase-14, SULFATE ION, anti_MT1-MMP Heavy chain, ... 著者 Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Moreno, v, Cuiniasse, P, Dive, V, Arroyo, A.G, Sagi, I, Israel Structural Proteomics Center (ISPC) 登録日 2014-07-22 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
4RBP	Crystal structure of HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomanose 分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, GLYCEROL, ... 著者 Stanfield, R.L, Wilson, I.A, De Castro, C, Marzaioli, A.M, Pantophlet, R. 登録日 2014-09-12 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose. Glycobiology, 25, 2015
3F12	Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus 分子名称: 8f9 Fab, M2J1 Fab 著者 Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. 登録日 2008-10-27 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
6CT7	Fab of anti-a-synuclein antibody BIIB054 in complex with acetylated a-synuclein peptide (1-10) 分子名称: ACE-MET-ASP-VAL-PHE-MET-LYS-GLY-LEU-SER-LYS, BIIB054 Fab heavy chain, BIIB054 Fab light chain, ... 著者 Arndt, J.W. 登録日 2018-03-22 公開日 2018-12-19 最終更新日 2018-12-26 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models. Neurobiol. Dis., 124, 2018
5D8J	Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes. 分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ... 著者 Doyle, C, Birrane, G. 登録日 2015-08-17 公開日 2016-01-13 最終更新日 2017-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015
4R26	Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody 分子名称: GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain 著者 Garces, F, Kong, L, Wilson, I.A. 登録日 2014-08-08 公開日 2014-10-08 最終更新日 2017-06-21 実験手法 X-RAY DIFFRACTION (2.4969 Å) 主引用文献 Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
6J9O	Crystal structure of a free scFv molecule from a group 2 influenza A viruses HA binding antibody AF4H1K1 分子名称: Heavy chain of AF4H1K1 scFv, Light chain of AF4H1K1 scFv 著者 Xiao, H.X, Qi, J.X, Gao, F.G. 登録日 2019-01-23 公開日 2020-01-29 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.397 Å) 主引用文献 Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses. Cell Discov, 5, 2019
6IEB	Structure of RVFV Gn and human monoclonal antibody R15 分子名称: NSmGnGc, R15 H chain, R15 L chain 著者 Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. 登録日 2018-09-13 公開日 2019-04-10 最終更新日 2019-07-10 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus. Nat Microbiol, 4, 2019
2DLF	HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 6.75 分子名称: PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S) (HEAVY CHAIN)), PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S)-KAPPA (LIGHT CHAIN)), SULFATE ION 著者 Nakasako, M, Takahashi, H, Shimada, I, Arata, Y. 登録日 1998-12-17 公開日 1999-12-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody. J.Mol.Biol., 291, 1999
4UAO	Crystal structure of Apical Membrane Antigen 1 from Plasmodium Knowlesi in complex with an invasion inhibitory antibody 分子名称: Apical merozoite antigen 1, immunoglobulin R31C2 VH and CH1 regions, immunoglobulin R31C2 light chain 著者 Vulliez-Le Normand, B, Saul, F.A, Bentley, G.A. 登録日 2014-08-11 公開日 2015-04-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Plasmodium knowlesi Apical Membrane Antigen 1 and Its Complex with an Invasion-Inhibitory Monoclonal Antibody. Plos One, 10, 2015
6P8M	Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... 著者 Weidle, C, Pancera, M. 登録日 2019-06-07 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.594 Å) 主引用文献 Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Rep, 29, 2019
6II4	Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14 分子名称: Heavy chain of L4A-14 Fab, Hemagglutinin, Light chain of L4A-14 Fab 著者 Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. 登録日 2018-10-03 公開日 2018-10-24 最終更新日 2019-02-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
1VFA	BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION 分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) 著者 Bhat, T.N, Poljak, R.J. 登録日 1993-12-03 公開日 1994-05-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc.Natl.Acad.Sci.USA, 91, 1994
1TOR	MOLECULAR DYNAMICS SIMULATION FROM 2D-NMR DATA OF THE FREE ACHR MIR DECAPEPTIDE AND THE ANTIBODY-BOUND [A76]MIR ANALOGUE 分子名称: ACETYLCHOLINE RECEPTOR, MAIN IMMUNOGENIC REGION 著者 Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T. 登録日 1995-10-11 公開日 1996-03-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data. Biopolymers, 40, 1996
6CBV	Crystal structure of BRIL bound to an affinity matured synthetic antibody. 分子名称: BRIL, FORMIC ACID, GLYCEROL, ... 著者 Mukherjee, S, Skrobek, B, Kossiakoff, A.A. 登録日 2018-02-05 公開日 2019-02-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.872 Å) 主引用文献 Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11, 2020
1VFB	BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION 分子名称: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) 著者 Bhat, T.N, Poljak, R.J. 登録日 1993-12-03 公開日 1994-05-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc.Natl.Acad.Sci.USA, 91, 1994

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