3F12

Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus

Summary for 3F12

Entry DOI	10.2210/pdb3f12/pdb
Related	3EYF 3EYO 3EYQ
Descriptor	M2J1 Fab, 8f9 Fab (2 entities in total)
Functional Keywords	human cytomegalovirus, antibody, germline, immunoglobulin domain, immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	99132.57
Authors	Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. (deposition date: 2008-10-27, release date: 2009-09-15, Last modification date: 2023-09-06)
Primary citation	Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27:2592-2602, 2008 Cited by PubMed: 18772881 DOI: 10.1038/emboj.2008.179 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation