3EYF
Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide
Summary for 3EYF
Entry DOI | 10.2210/pdb3eyf/pdb |
Related | 3EYO 3EYQ 3F12 |
Descriptor | 8f9 Fab, AD-2, Synthetic peptide, ... (5 entities in total) |
Functional Keywords | cytomegalovirus, antibody, immunoglobulin domain, cleavage on pair of basic residues, envelope protein, glycoprotein, host-virus interaction, membrane, transmembrane, virion, immune system |
Biological source | Homo sapiens More |
Cellular location | Virion membrane ; Single-pass type I membrane protein : P13201 |
Total number of polymer chains | 6 |
Total formula weight | 101966.14 |
Authors | Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. (deposition date: 2008-10-20, release date: 2008-12-16, Last modification date: 2023-09-06) |
Primary citation | Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27:2592-2602, 2008 Cited by PubMed: 18772881DOI: 10.1038/emboj.2008.179 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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