3EYQ

Crystal structure of MJ5 Fab, a germline antibody variant of anti-human cytomegalovirus antibody 8f9

Summary for 3EYQ

• Entry DOI: 10.2210/pdb3eyq/pdb
• Related: 3EYF 3EYO 3F12
• Descriptor: M2J5 Fab, 8f9 Fab (3 entities in total)
• Functional Keywords: human cytomegalovirus, antibody, immunoglobulin domain, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 49521.25

Authors

Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. (deposition date: 2008-10-21, release date: 2008-12-16, Last modification date: 2023-09-06)

• Primary citation: Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W.; Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.; Embo J., 27:2592-2602, 2008; PubMed: 18772881; DOI: 10.1038/emboj.2008.179

Experimental method

X-RAY DIFFRACTION (2.4 Å)