6P8M

Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C

Summary for 6P8M

• Entry DOI: 10.2210/pdb6p8m/pdb
• Descriptor: Gp120, CHLORIDE ION, P-p3b3 Heavy Chain, ... (11 entities in total)
• Functional Keywords: antibody, 426c, immunization, immune system
• Biological source: Human immunodeficiency virus (HIV-1); More
• Total number of polymer chains: 3
• Total formula weight: 91210.47

Authors

Weidle, C.,Pancera, M. (deposition date: 2019-06-07, release date: 2019-11-20, Last modification date: 2023-10-11)

• Primary citation: Parks, K.R.,MacCamy, A.J.,Trichka, J.,Gray, M.,Weidle, C.,Borst, A.J.,Khechaduri, A.,Takushi, B.,Agrawal, P.,Guenaga, J.,Wyatt, R.T.,Coler, R.,Seaman, M.,LaBranche, C.,Montefiori, D.C.,Veesler, D.,Pancera, M.,McGuire, A.,Stamatatos, L.; Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.; Cell Rep, 29:3060-3072.e7, 2019; PubMed: 31801073; DOI: 10.1016/j.celrep.2019.10.071

Experimental method

X-RAY DIFFRACTION (3.594 Å)