8Q75
 
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8Q76
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8Q73
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8UIY
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3HPR
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8UIZ
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8UJ9
 | | In situ human P state 80S ribosome | | 分子名称: | 18S rRNA [Homo sapiens], 28S rRNA [Homo sapiens], 40S ribosomal protein S10, ... | | 著者 | Wei, Z, Yong, X. | | 登録日 | 2023-10-11 | | 公開日 | 2025-04-16 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | In situ human P state 80S ribosome
To Be Published
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1ZDU
 | | The Crystal Structure of Human Liver Receptor Homologue-1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2, ... | | 著者 | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | | 登録日 | 2005-04-14 | | 公開日 | 2005-05-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Proc.Natl.Acad.Sci.USA, 102, 2005
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7TNI
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4JK2
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7SIN
 | | Structure of negative allosteric modulator-bound inactive human calcium-sensing receptor | | 分子名称: | 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, Isoform 1 of Extracellular calcium-sensing receptor | | 著者 | Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R. | | 登録日 | 2021-10-14 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7SIL
 | | Structure of positive allosteric modulator-bound active human calcium-sensing receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | | 著者 | Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R. | | 登録日 | 2021-10-14 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5ISO
 | | STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) | | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | | 著者 | Xiao, B, Hubbard, J.A, Gamblin, S.J. | | 登録日 | 2016-03-15 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991)
To Be Published
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6NZD
 | | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | | 分子名称: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | | 著者 | Fromm, S.A, Young, L.N, Hurley, J.H. | | 登録日 | 2019-02-13 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Science, 366, 2019
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1NZ1
 | | Solution structure of the S. cerevisiae U6 Intramolecular stem-loop containing an SP phosphorothioate at nucleotide U80 | | 分子名称: | SP U6 Intramolecular Stem-Loop RNA | | 著者 | Reiter, N.J, Nikstad, L.J, Allman, A.M, Johnson, R.J, Butcher, S.E. | | 登録日 | 2003-02-14 | | 公開日 | 2003-05-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the U6 RNA intramolecular stem-loop harboring an
S(P)-phosphorothioate modification.
RNA, 9, 2003
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7SIM
 | | Structure of positive allosteric modulator-free active human calcium-sensing receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R. | | 登録日 | 2021-10-14 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4KMU
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7U7N
 | | IL-27 quaternary receptor signaling complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | | 著者 | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | | 登録日 | 2022-03-07 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structure of the IL-27 quaternary receptor signaling complex.
Elife, 11, 2022
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8RAP
 | | Structure of Sen1-ADP.BeF3 bound RNA Polymerase II pre-termination complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Rengachari, S, Lidscreiber, M, Cramer, P. | | 登録日 | 2023-12-01 | | 公開日 | 2024-10-30 | | 最終更新日 | 2025-02-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Mechanism of polyadenylation-independent RNA polymerase II termination.
Nat.Struct.Mol.Biol., 32, 2025
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8RAM
 | | Structure of Sen1 bound RNA Polymerase II pre-termination complex | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Rengachari, S, Lidscreiber, M, Cramer, P. | | 登録日 | 2023-12-01 | | 公開日 | 2024-10-30 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of polyadenylation-independent RNA polymerase II termination.
Nat.Struct.Mol.Biol., 32, 2025
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5BZX
 | | Crystal structure of human phosphatase PTEN treated with a bisperoxovanadium complex | | 分子名称: | L(+)-TARTARIC ACID, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, VANADATE ION | | 著者 | Lee, C.-U, Bier, D, Hennig, S, Grossmann, T.N. | | 登録日 | 2015-06-11 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.
Angew.Chem.Int.Ed.Engl., 54, 2015
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2BE4
 | | X-RAY STRUCTURE AN EF-HAND PROTEIN FROM DANIO RERIO Dr.36843 | | 分子名称: | hypothetical protein LOC449832 | | 著者 | Wesenberg, G.E, Phillips Jr, G.N, Han, B.W, Bitto, E, Bingman, C.A, Bae, E, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2005-10-21 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray structure of Danio rerio secretagogin: A hexa-EF-hand calcium sensor.
Proteins, 76, 2009
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2BDN
 | | Crystal structure of human MCP-1 bound to a blocking antibody, 11K2 | | 分子名称: | Antibody heavy chain 11K2, Antibody light chain 11K2, Small inducible cytokine A2 | | 著者 | Boriack-Sjodin, P.A, Rushe, M, Reid, C, Jarpe, M, van Vlijmen, H, Bailly, V. | | 登録日 | 2005-10-20 | | 公開日 | 2006-06-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody.
Protein Eng.Des.Sel., 19, 2006
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1OEZ
 | | Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase | | 分子名称: | SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | | 著者 | Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Elam, J.S, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | | 登録日 | 2003-04-02 | | 公開日 | 2003-05-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Amyloid-Like Filaments and Water-Filled Nanotubes Formed by Sod1 Mutant Proteins Linked to Familial Als
Nat.Struct.Biol., 10, 2003
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8QV5
 | | Structure of human SPNS2 in LMNG | | 分子名称: | Nanobody D12, Sphingosine-1-phosphate transporter SPNS2 | | 著者 | Li, H.Z, Pike, A.C.W, McKinley, G, Mukhopadhyay, S.M.M, Moreau, C, Scacioc, A, Abrusci, P, Borkowska, O, Chalk, R, Stefanic, S, Burgess-Brown, N, Duerr, K.L, Sauer, D.B. | | 登録日 | 2023-10-17 | | 公開日 | 2025-02-19 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2.
Nat Commun, 16, 2025
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