2BDN

Crystal structure of human MCP-1 bound to a blocking antibody, 11K2

Summary for 2BDN

Entry DOI	10.2210/pdb2bdn/pdb
Descriptor	Small inducible cytokine A2, Antibody light chain 11K2, Antibody heavy chain 11K2, ... (4 entities in total)
Functional Keywords	antibody-antigen complex, immune system
Biological source	Mus musculus (house mouse) More
Cellular location	Secreted : P13500
Total number of polymer chains	3
Total formula weight	55396.86
Authors	Boriack-Sjodin, P.A.,Rushe, M.,Reid, C.,Jarpe, M.,van Vlijmen, H.,Bailly, V. (deposition date: 2005-10-20, release date: 2006-06-13, Last modification date: 2024-04-03)
Primary citation	Reid, C.,Rushe, M.,Jarpe, M.,van Vlijmen, H.,Dolinski, B.,Qian, F.,Cachero, T.G.,Cuervo, H.,Yanachkova, M.,Nwankwo, C.,Wang, X.,Etienne, N.,Garber, E.,Bailly, V.,de Fougerolles, A.,Boriack-Sjodin, P.A. Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody. Protein Eng.Des.Sel., 19:317-324, 2006 Cited by PubMed: 16682434 DOI: 10.1093/protein/gzl015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation