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7A3N
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Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10
分子名称: CALCIUM ION, Core protein, EDE1 C10 Fab
著者Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A.
登録日2020-08-18
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
7A3T
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Crystal structure of dengue 3 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8
分子名称: Core protein, EDE1 C8 antibody Fab fragment, GLYCEROL, ...
著者Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A.
登録日2020-08-18
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
7A3U
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Crystal structure of Zika virus envelope glycoprotein in complex with the divalent F(ab')2 fragment of the broadly neutralizing human antibody EDE1 C10
分子名称: EDE1 C10 antibody divalent F(ab')2 fragment, EDE1 C10 divalent F(ab')2 fragment, Envelope protein
著者Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A.
登録日2020-08-18
公開日2021-12-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
4XJE
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BU of 4xje by Molmil
CRYSTAL STRUCTURE OF ANT(2") IN COMPLEX WITH AMP AND TOBRAMYCIN
分子名称: ADENOSINE MONOPHOSPHATE, AadB, GLYCEROL, ...
著者Rodionov, D, Bassenden, A.V, Berghuis, A.M.
登録日2015-01-08
公開日2016-01-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study.
Acs Chem.Biol., 2020
7S68
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Structure of human PARP1 domains (Zn1, Zn3, WGR and HD) bound to a DNA double strand break.
分子名称: DNA (5'-D(*GP*CP*CP*TP*GP*CP*AP*GP*GP*C)-3'), Fusion of PARP1 zinc fingers 1 and 3 (Zn1, Zn3), ...
著者Rouleau-Turcotte, E, Pascal, J.M.
登録日2021-09-13
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery.
Mol.Cell, 82, 2022
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
分子名称: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2017-11-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6F08
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14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1)
分子名称: 14-3-3 protein zeta/delta, PENTAETHYLENE GLYCOL, Son of sevenless homolog 1
著者Ballone, A, Centorrino, F, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of 14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1).
J. Struct. Biol., 202, 2018
7AXZ
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Ku70/80 complex apo form
分子名称: X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
著者Hnizda, A, Tesina, P, Novak, P, Blundell, T.L.
登録日2020-11-10
公開日2021-02-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SAP domain forms a flexible part of DNA aperture in Ku70/80.
Febs J., 288, 2021
7Z13
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S. cerevisiae CMGE dimer nucleating origin DNA melting
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ...
著者Lewis, J.S, Sousa, J.S, Costa, A.
登録日2022-02-24
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature, 606, 2022
1DU0
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BU of 1du0 by Molmil
ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), ENGRAILED HOMEODOMAIN
著者Grant, R.A, Rould, M.A, Klemm, J.D, Pabo, C.O.
登録日2000-01-13
公開日2000-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
5YIU
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Caulobacter crescentus GcrA DNA-binding domain (DBD)
分子名称: Cell cycle regulatory protein GcrA
著者Wu, X, Zhang, Y.
登録日2017-10-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
5YIW
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Caulobacter crescentus GcrA DNA-binding domain (DBD) in complex with methylated dsDNA (crystal form 2)
分子名称: (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*CP*TP*GP*(6MA)P*TP*TP*CP*GP*C)-3'), ...
著者Wu, X, Zhang, Y.
登録日2017-10-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
3MRJ
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BU of 3mrj by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide V5M variant
分子名称: 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide V5M variant
To be Published
6F09
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Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide
分子名称: 14-3-3 protein zeta/delta, Ubiquitin carboxyl-terminal hydrolase 8
著者Centorrino, F, Ballone, A, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Biophysical and structural insight into the USP8/14-3-3 interaction.
FEBS Lett., 592, 2018
5YIV
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BU of 5yiv by Molmil
Caulobacter crescentus GcrA DNA-binding domain(DBD) in complex with methylated dsDNA(crystal form 1)
分子名称: Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*GP*(6MA)P*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*(6MA)P*TP*TP*CP*G)-3')
著者Wu, X, Zhang, Y.
登録日2017-10-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.914 Å)
主引用文献Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
3ICH
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BU of 3ich by Molmil
Crystal structure of cyclophilin B at 1.2 A resolution
分子名称: Peptidyl-prolyl cis-trans isomerase B
著者Kozlov, G, Gehring, K.
登録日2009-07-17
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain.
J.Biol.Chem., 285, 2010
3ICI
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BU of 3ici by Molmil
Crystal structure of cyclophilin B in complex with calmegin fragment
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Calnexin, Peptidyl-prolyl cis-trans isomerase B, ...
著者Kozlov, G, Gehring, K.
登録日2009-07-17
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain.
J.Biol.Chem., 285, 2010
6FNC
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Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ...
著者Bier, D, Ottann, C.
登録日2018-02-02
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
6FN9
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Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins
分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ...
著者Bier, D, Ottmann, C.
登録日2018-02-02
公開日2018-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.
Chemistry, 24, 2018
7DOC
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BU of 7doc by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 5
分子名称: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Core protein, Genome polyprotein, ...
著者Quek, J.P.
登録日2020-12-14
公開日2021-04-14
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.
Acs Med.Chem.Lett., 12, 2021
3IDB
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BU of 3idb by Molmil
Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S.
登録日2009-07-20
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009
6YOS
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BU of 6yos by Molmil
Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 pS617 peptide
分子名称: 14-3-3 protein zeta/delta, Glucocorticoid receptor,Glucocorticoid receptor
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-15
公開日2021-03-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
6YMO
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Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pS617 peptide
分子名称: 14-3-3 protein zeta/delta, 2-HYDROXYBENZOIC ACID, Glucocorticoid receptor, ...
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-09
公開日2021-03-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
6YO8
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BU of 6yo8 by Molmil
Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 peptide
分子名称: 14-3-3 protein zeta/delta, Glucocorticoid receptor
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-14
公開日2021-03-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
3IDC
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BU of 3idc by Molmil
Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Brown, S.H.J, Wu, J, Kim, C, Alberto, K, Taylor, S.S.
登録日2009-07-20
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.
J.Mol.Biol., 393, 2009

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