7DOC

Crystal structure of Zika NS2B-NS3 protease with compound 5

Summary for 7DOC

Entry DOI	10.2210/pdb7doc/pdb
Descriptor	Core protein, Genome polyprotein, Serine protease subunit NS2B, ... (9 entities in total)
Functional Keywords	viral protease, protease inhibitor complex, viral protein
Biological source	Zika virus (ZIKV) More
Total number of polymer chains	9
Total formula weight	83940.59
Authors	Quek, J.P. (deposition date: 2020-12-14, release date: 2021-04-14, Last modification date: 2023-11-29)
Primary citation	Patil, N.A.,Quek, J.P.,Schroeder, B.,Morewood, R.,Rademann, J.,Luo, D.,Nitsche, C. 2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease. Acs Med.Chem.Lett., 12:732-737, 2021 Cited by PubMed: 34055219 DOI: 10.1021/acsmedchemlett.0c00657 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.904 Å)

Structure validation