7DOC
Crystal structure of Zika NS2B-NS3 protease with compound 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (A, G) | Core protein | polymer | 39 | 4347.7 | 2 | UniProt (A0A2R4LVW1) Pfam (PF01002) UniProt (by SIFTS) (Q32ZE1) | Zika virus (ZIKV) | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 2 | B (B) | Core protein | polymer | 153 | 16342.6 | 1 | UniProt (A0A142IX72) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) | Zika virus (ZIKV) | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 3 | C (C) | Genome polyprotein | polymer | 38 | 4218.5 | 1 | UniProt (Q32ZE1) | Zika virus (ZIKV) | |
| 4 | D (D) | Core protein | polymer | 152 | 16213.5 | 1 | UniProt (A0A142IX72) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) | Zika virus (ZIKV) | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 5 | E (E) | Serine protease subunit NS2B | polymer | 39 | 4361.7 | 1 | UniProt (Q32ZE1) Pfam (PF01002) | Zika virus (ZIKV) | Flavivirin protease NS2B regulatory subunit,Non-structural protein 2B |
| 6 | F (F) | Core protein | polymer | 158 | 16944.3 | 1 | UniProt (A0A142IX72) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) | Zika virus (ZIKV) | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 7 | H (H) | Genome polyprotein | polymer | 153 | 16370.7 | 1 | UniProt (H8XX12) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) | Zika virus (ZIKV) | NS3 Protease |
| 8 | I (I) | 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE | polymer | 5 | 810.0 | 1 | synthetic construct | ||
| 9 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 83956.6 | |
| All* | Total formula weight | 83956.6 |
