6F09

Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide

Summary for 6F09

Descriptor14-3-3 protein zeta/delta, Ubiquitin carboxyl-terminal hydrolase 8 (3 entities in total)
Functional Keywords14-3-3, usp8, phosphosite, binary complex protein-peptide, signaling protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  P63104 P40818
Total number of polymer chains8
Total molecular weight111689.88
Authors
Centorrino, F.,Ballone, A.,Ottmann, C.,Guo, S.,Leysen, S. (deposition date: 2017-11-17, release date: 2018-03-07, Last modification date: 2018-04-25)
Primary citation
Centorrino, F.,Ballone, A.,Wolter, M.,Ottmann, C.
Biophysical and structural insight into the USP8/14-3-3 interaction.
FEBS Lett., 592:1211-1220, 2018
PubMed: 29473952 (PDB entries with the same primary citation)
DOI: 10.1002/1873-3468.13017
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.594 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.225201.3%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution