7Z13

S. cerevisiae CMGE dimer nucleating origin DNA melting

This is a non-PDB format compatible entry.

Summary for 7Z13

• Entry DOI: 10.2210/pdb7z13/pdb
• Related: 7QHS
• EMDB information: 14439
• Descriptor: DNA replication licensing factor MCM2, DNA replication complex GINS protein SLD5, Cell division control protein 45, ... (19 entities in total)
• Functional Keywords: dna replication, helicase, initiation, dna origin, replication
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 28
• Total formula weight: 2297536.23

Authors

Lewis, J.S.,Sousa, J.S.,Costa, A. (deposition date: 2022-02-24, release date: 2022-06-15, Last modification date: 2022-07-06)

• Primary citation: Lewis, J.S.,Gross, M.H.,Sousa, J.,Henrikus, S.S.,Greiwe, J.F.,Nans, A.,Diffley, J.F.X.,Costa, A.; Mechanism of replication origin melting nucleated by CMG helicase assembly.; Nature, 606:1007-1014, 2022; PubMed: 35705812; DOI: 10.1038/s41586-022-04829-4

Experimental method

ELECTRON MICROSCOPY (3.4 Å)