PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

5YTK	Crystal structure of SIRT3 bound to a leucylated AceCS2 分子名称: AceCS2-KLeu, LEUCINE, LYSINE, ... 著者 Li, J, Gong, W, Xu, Y. 登録日 2017-11-18 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations Cell Metab., 27, 2018
5Y7N	Crystal structure of AKR1B10 in complex with NADP+ and Androst-4-ene-3-beta-6-alpha-diol 分子名称: (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hong, Z, Liping, Z, Cuiyun, L, Wei, Z. 登録日 2017-08-17 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural determinants for the inhibition of AKR1B10 by steroids To Be Published
2N3A	Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404) 分子名称: PC4 and SFRS1-interacting protein, Pogo transposable element with ZNF domain 著者 Tesina, P, Cermakova, K, Horejsi, M, Prochazkova, K, Fabry, M, Sharma, S, Christ, F, Demeulemeester, J, Debyser, Z, De Rijck, J, Veverka, V, Rezacova, P. 登録日 2015-05-26 公開日 2015-08-19 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif. Nat Commun, 6, 2015
6F63	Crystal structure of the SYCP1 C-terminal back-to-back assembly 分子名称: Synaptonemal complex protein 1 著者 Dunce, J.M, Millan, C, Uson, I, Davies, O.R. 登録日 2017-12-04 公開日 2018-06-06 最終更新日 2020-04-22 実験手法 X-RAY DIFFRACTION (2.154 Å) 主引用文献 Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25, 2018
5YKE	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.11 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YDZ	structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 1 分子名称: mammalian endo-lysosomal TRPML1 channel 著者 Yang, M, Gao, N. 登録日 2017-09-15 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
6FCF	CHK1 KINASE IN COMPLEX WITH COMPOUND 44 分子名称: 4-[[(2~{R},3~{S})-2-methylpiperidin-3-yl]amino]-2-phenyl-thieno[3,2-c]pyridine-7-carboxamide, SULFATE ION, Serine/threonine-protein kinase Chk1 著者 Read, J.A, Breed, J. 登録日 2017-12-20 公開日 2018-01-17 最終更新日 2018-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J. Med. Chem., 61, 2018
6CA6	Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody. 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_35S heavy chain, ... 著者 Murrell, S, Wilson, I.A. 登録日 2018-01-29 公開日 2018-06-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23, 2018
6CAD	Crystal structure of RAF kinase domain bound to the inhibitor 2a 分子名称: 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Serine/threonine-protein kinase B-raf 著者 Maisonneuve, P, Kurinov, I, Assadieskandar, A, Yu, C, Liu, X, Chen, Y.-C, Prakash, G.K.S, Zhang, C, SIcheri, F. 登録日 2018-01-30 公開日 2018-02-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Effects of rigidity on the selectivity of protein kinase inhibitors. Eur J Med Chem, 146, 2018
6F8U	Crystal structure of the PDE4D catalytic domain in complex with GEBR-20b 分子名称: 2-[(~{E})-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]methylideneamino]oxy-1-[(2~{R},6~{R})-2,6-dimethylmorpholin-4-yl]ethanone, MAGNESIUM ION, ZINC ION, ... 著者 Prosdocimi, T, Donini, S, Parisini, E. 登録日 2017-12-13 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds. Biochemistry, 57, 2018
6FFB	17beta-hydroxysteroid dehydrogenase 14 variant S205 - mutant Q148A - in complex with a nonsteroidal inhibitor 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... 著者 Bertoletti, N, Heine, A, Klebe, G, Marchais-Oberwinkler, S. 登録日 2018-01-05 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Mutational and structural studies uncover crucial amino acids determining activity and stability of 17 beta-HSD14. J.Steroid Biochem.Mol.Biol., 189, 2019
6BNH	Solution NMR structures of BRD4 ET domain with JMJD6 peptide 分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4 著者 Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L. 登録日 2017-11-16 公開日 2017-12-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4. Sci Rep, 7, 2017
6C00	Solution structure of translation initiation factor 1 from Clostridium difficile 分子名称: Translation initiation factor IF-1 著者 Zhang, Y, Aguilar, F. 登録日 2017-12-26 公開日 2019-01-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 1H,13C and15N resonance assignments and structure prediction of translation initiation factor 1 from Clostridium difficile. Biomol.Nmr Assign., 13, 2019
5BWL	Crystal Structure of SIRT5 in Complex with a Coumarin-Labelled Succinyl Peptide 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, Coumarin-labelled succinyl peptide, NAD-dependent protein deacylase sirtuin-5, ... 著者 Gai, W, Jiang, H, Liu, D. 登録日 2015-06-08 公開日 2016-07-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.548 Å) 主引用文献 Crystal Structure of SIRT5 in Complex with a Coumarin-Labelled Succinyl Peptide To be published
5BX6	PKA in complex with a halogenated phthalazinone fragment compound. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-chlorophthalazin-1(2H)-one, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Narayanan, D, Alam, K.A, Engh, R.A. 登録日 2015-06-08 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 PKA based studies of ligand interactions with a methionine gatekeeper. To Be Published
6F5X	Crystal structure of the SYCP1 N-terminal head-to-head assembly in closed conformation 分子名称: IODIDE ION, Synaptonemal complex protein 1, TRIETHYLENE GLYCOL 著者 Ratcliff, M, Dunce, J.M, Davies, O.R. 登録日 2017-12-04 公開日 2018-06-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25, 2018
5YPZ	Crystal structure of minor pilin CofB from CFA/III complexed with N-terminal peptide fragment of CofJ 分子名称: CofB, CofJ 著者 Oki, H, Kawahara, K, Maruno, T, Imai, T, Muroga, Y, Fukakusa, S, Iwashita, T, Kobayashi, Y, Matsuda, S, Kodama, T, Iida, T, Yoshida, T, Ohkubo, T, Nakamura, S. 登録日 2017-11-04 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.521 Å) 主引用文献 Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenicEscherichia colicolonization. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CNQ	MBD2 in complex with methylated DNA 分子名称: DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION 著者 Liu, K, Xu, C, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-03-08 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
5YH2	The structure of DrFam20C1 and hFam20A complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Family with sequence similarity 20, member Ca, ... 著者 Zhang, H, Xiao, J. 登録日 2017-09-27 公開日 2018-04-11 最終更新日 2018-04-25 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structure and evolution of the Fam20 kinases Nat Commun, 9, 2018
6F4Q	Human JMJD5 (Q275C) in complex with Mn(II), NOG and RPS6-A138C (129-144) (complex-2) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 40S ribosomal protein S6, GLYCEROL, ... 著者 Chowdhury, R, Islam, M.S, Schofield, C.J. 登録日 2017-11-29 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 JMJD5 is a human arginyl C-3 hydroxylase. Nat Commun, 9, 2018
4M7R	Crystal structure of the N-terminal methyltransferase-like domain of anamorsin 分子名称: Anamorsin, MERCURY (II) ION 著者 Song, G, Liu, Z.-J. 登録日 2013-08-12 公開日 2013-10-30 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Crystal structure of the N-terminal methyltransferase-like domain of anamorsin. Proteins, 82, 2014
6F57	Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA 分子名称: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ... 著者 Zhang, Z.M, Song, J. 登録日 2017-12-01 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.098 Å) 主引用文献 Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
6F7P	Crystal structure of Human ARS2 residues 147-270 + 408-763 分子名称: Serrate RNA effector molecule homolog 著者 Cusack, S, Schulze, W.M. 登録日 2017-12-11 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting. Nat Commun, 9, 2018
6F8X	Crystal structure of the PDE4D catalytic domain in complex with GEBR-26g 分子名称: 1,2-ETHANEDIOL, 2-[(5~{R})-3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-1,2-oxazol-5-yl]-~{N},~{N}-bis(2-hydroxyethyl)ethanamide, DIMETHYL SULFOXIDE, ... 著者 Prosdocimi, T, Donini, S, Parisini, E. 登録日 2017-12-13 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds. Biochemistry, 57, 2018
6F9O	Crystal structure of cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Haloalkane dehalogenase, ... 著者 Tratsiak, K, Prudnikova, T, Drienovska, I, Damborsky, J, Brynda, J, Pachl, P, Kuty, M, Chaloupkova, R, Kuta Smatanova, I, Rezacova, P. 登録日 2017-12-15 公開日 2019-02-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Crystal structure of the cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5. Acta Crystallogr.,Sect.F, 75, 2019

<397398399400401402403404405406407408409410411412>