5YTK

Crystal structure of SIRT3 bound to a leucylated AceCS2

Summary for 5YTK

• Entry DOI: 10.2210/pdb5ytk/pdb
• Descriptor: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, AceCS2-KLeu, ZINC ION, ... (6 entities in total)
• Functional Keywords: dna-dependent deacetylase sirtuin-3, leucylated acecs2, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion matrix : Q9NTG7
• Total number of polymer chains: 10
• Total formula weight: 188193.80

Authors

Li, J.,Gong, W.,Xu, Y. (deposition date: 2017-11-18, release date: 2017-12-27, Last modification date: 2023-11-22)

• Primary citation: He, X.D.,Gong, W.,Zhang, J.N.,Nie, J.,Yao, C.F.,Guo, F.S.,Lin, Y.,Wu, X.H.,Li, F.,Li, J.,Sun, W.C.,Wang, E.D.,An, Y.P.,Tang, H.R.,Yan, G.Q.,Yang, P.Y.,Wei, Y.,Mao, Y.Z.,Lin, P.C.,Zhao, J.Y.,Xu, Y.,Xu, W.,Zhao, S.M.; Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations; Cell Metab., 27:151-166.e6, 2018; PubMed: 29198988; DOI: 10.1016/j.cmet.2017.10.015

Experimental method

X-RAY DIFFRACTION (2.7 Å)