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5YKE

Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)

Summary for 5YKE
Entry DOI10.2210/pdb5yke/pdb
EMDB information6689 6831 8470
DescriptorATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide (3 entities in total)
Functional Keywordskatp, channel, glibenclamide, sulfonylurea, membrane protein
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains8
Total formula weight885621.02
Authors
Chen, L.,Wu, J.X. (deposition date: 2017-10-14, release date: 2018-04-18, Last modification date: 2018-06-13)
Primary citationWu, J.X.,Ding, D.,Wang, M.,Kang, Y.,Zeng, X.,Chen, L.
Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9:553-567, 2018
Cited by
PubMed: 29594720
DOI: 10.1007/s13238-018-0530-y
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.11 Å)
Structure validation

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